Status:

UNKNOWN

Surgical Ovarian Drilling Versus Hormonal Treatment for Infertility Associated to PolyCystic Ovaries Syndrome (PCOS)

Lead Sponsor:

Assistance Publique - Hôpitaux de Paris

Collaborating Sponsors:

Hopital Antoine Beclere

Hôpital Jean Verdier

Conditions:

Polycystic Ovary Syndrome

Eligibility:

FEMALE

18-36 years

Phase:

PHASE4

Brief Summary

PolysCsytic Ovaries Syndrome (PCOS) is the most frequent endocrinopathy. The first stage of infertility treatment is Clomiphene Citrate which leads to 50 % pregnancies. In case of failure, it is possi...

Detailed Description

PolysCsytic Ovaries Syndrome (PCOS) is the most frequent endocrinopathy. The first stage of infertility treatment is Clomiphene Citrate which leads to 50 % pregnancies. In case of failure, it is possi...

Eligibility Criteria

Inclusion

  • Age between 18 and 36 years old
  • Female patient with PCOS (Rotterdam criteria)
  • Failure of treatment with Clomiphene Citrate
  • Informed consent
  • Female patient with medical assurance
  • Patient in failure with PCOS and Clomiphene citrate

Exclusion

  • Female patient is over 36 years old
  • Thyroid disease (4\<TSH\<0.3 mUI/L)
  • Virilizing tumor
  • FERTILOSCOPY non possible (Douglas cul de sac clinically fixed)
  • Anormality of SPERMOGRAM (abnormal time of migration of survival)
  • Prolactin \> 1.5 N
  • Anormality of 17-OH Progesterone (\<2 ng/mL)
  • Fallopian tubes non permeable TMS\< 5 Millions
  • Female patient participant or have been participated to another clinical trial during the last month before the inclusion
  • Female patient without medical assurance

Key Trial Info

Start Date :

October 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2011

Estimated Enrollment :

252 Patients enrolled

Trial Details

Trial ID

NCT00378729

Start Date

October 1 2006

End Date

October 1 2011

Last Update

October 4 2011

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hopital Antoine Beclere

Clamart, France, 92170