Status:
COMPLETED
Sleepiness and the Risk of Falling
Lead Sponsor:
National Institute on Aging (NIA)
Collaborating Sponsors:
National Center for Research Resources (NCRR)
Conditions:
Aging
Balance
Eligibility:
All Genders
18-85 years
Phase:
NA
Brief Summary
The purpose of this project is to examine the impact of sleeping pills and waking up in the middle of the night on walking balance and cognitive function, to identify risk factors for falls in older a...
Detailed Description
Awakening from sleep is well documented to impair cognitive performance in young adults. This phenomenon, called sleep inertia, has been reported to impair performance just as much as one night of tot...
Eligibility Criteria
Inclusion
- Males and females
- Aged 18 to 35, or 60 to 85
- Lived at Denver altitude or higher for at least one year
- Stable treated diseases: thyroid dysfunction (including hypothyroidism and hyperthyroidism), hypertension, hypercholesterolemia, urinary incontinence, prostate enlargement, gastroesophageal reflux disease, irritable bowel syndrome
Exclusion
- Aged 36 to 59, under 18, or over 85
- BMI less than 18.6 or greater than 30 kg/m2, women below 95 pounds regardless of BMI
- Sleep duration is less than 5 or more than 9 hours
- Sensitivity to sleeping medications
- Night work in the preceding 6 months
- Transmeridian travel (across more than 2 time zones) in the last 1 month
- Bone mineral density DXA T-score of less than -1.75
- Orthostatic intolerance
- Prior history of falls in past year
- Prior history of injurious fall in past 5 years
- Hip fracture following a fall
- Difficulty rising from a sitting position without use of hands to push off
- Needing to walk slowly or with a wide base of support to maintain balance
- Hormone replacement therapy for less than 3 months
- Connective Tissue and Joint Disorders
- Neurologic Disorders
- Musculoskeletal Disorders
- Immune Disorders
- Sleep Disorders
- Chronobiologic Disorders
- Cardiovascular Disorders
- Respiratory Disorders
- Kidney and Urinary Tract Disorders
- Infectious Diseases
- Gastrointestinal Disorders
- Hematopoietic Disorders
- Neoplastic Diseases
- Endocrine and Metabolic Diseases
- Psychopathology
- Dementia
- Drug dependency
Key Trial Info
Start Date :
August 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT00383357
Start Date
August 1 2004
Last Update
September 20 2007
Active Locations (1)
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1
University of Colorado at Boulder
Boulder, Colorado, United States, 80309