Status:

COMPLETED

Congenital and Neonatal Malaria in Mali

Lead Sponsor:

National Institute of Allergy and Infectious Diseases (NIAID)

Conditions:

Malaria

Eligibility:

All Genders

Brief Summary

This study will look at blood samples taken from 300 preterm babies and newborns admitted for inpatient care at Hopital Gabriel Toure in Bamako, Mali, and to gather information that will help the inve...

Detailed Description

The purpose of this cross-sectional study is to determine the rate of congenital and acquired malaria in inpatient neonates at a tertiary pediatric hospital in Bamako, Mali. The primary study endpoint...

Eligibility Criteria

Inclusion

  • Neonates: 1) Preterm born before 37 weeks of pregnancy admitted for inpatient care at HGT or Neonates aged between 0 - 28 days admitted for inpatient care at HGT 2) Admission weight more than 2000 grams 3) Parental informed consent obtained and signed for infant participation Criteria for Mothers: - Consenting mother of an enrolled infant

Exclusion

  • Neonates: 1) Outpatient infant 2) Infant weighing less than 2000g 3) Infants presenting the following symptoms of critical condition: bradycardy, gasp, severely altered general condition 4) Presence of severe anemia 5) Infants who are judged by the study physicians to be unfit for enrollment for any reason 6) Informed consent denied Criteria for Mothers: 1) Mothers with severe malaria (2) 2) Mothers with an acute severe disease 3) Mothers who are judged by the study physician to be unfit for enrollment for any reason 4) Informed consent denied

Key Trial Info

Start Date :

October 1 2006

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 1 2009

Estimated Enrollment :

44 Patients enrolled

Trial Details

Trial ID

NCT00384267

Start Date

October 1 2006

End Date

April 1 2009

Last Update

November 11 2011

Active Locations (1)

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1

Hopital Gabriel Toure

Bamako, Mali