Status:
UNKNOWN
Fosamax for Childhood Cancer Survivors
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Osteoporosis
Eligibility:
All Genders
15+ years
Phase:
PHASE3
Brief Summary
Survivors of childhood cancers face a variety of long-term problems. The investigators' recent study found that osteoporosis and osteopenia were common among these patients. The factors leading to, as...
Detailed Description
The modern treatment for childhood malignancy includes surgery and chemoradiotherapy either individually or in combination. Despite the great achievement in improving patient survival, these treatment...
Eligibility Criteria
Inclusion
- Chinese patients who completed treatments for childhood cancers for at least 5 years
- Currently followed up in the Department of Paediatrics of Prince of Wales Hospital
- Younger than 18 years old at the time of diagnosis of underlying cancers
- Evidence of osteoporosis (i.e. BMD T- or Z-score \< -2.5 at lumbar spine)
- Older than 15 years of age at the time of recruitment
Exclusion
- Current treatment (i.e. within 6 months) with maintenance systemic or high-dose inhaled corticosteroids
- Subjects who cannot cooperate for BMD measurements
- Pregnant female patients
- Subjects with prior history of allergy to alendronate or in whom alendronate treatment is contraindicated
Key Trial Info
Start Date :
May 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2008
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00391404
Start Date
May 1 2006
End Date
October 1 2008
Last Update
May 23 2008
Active Locations (1)
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1
Prince of Wales Hospital, Shatin, N.T.
Hong Kong, Hong Kong