Status:

COMPLETED

Environmental Exposures, Genetics, and Exhaled Nitric Oxide in Pediatric Asthma

Lead Sponsor:

Children's Hospital Medical Center, Cincinnati

Collaborating Sponsors:

National Heart, Lung, and Blood Institute (NHLBI)

Conditions:

Asthma

Eligibility:

All Genders

6-12 years

Brief Summary

Asthma is one of the most common childhood diseases. It is chronic and often severely disabling. The amount of nitric oxide that is exhaled while breathing increases with airway inflammation, a sympto...

Detailed Description

Nitric oxide is a naturally occurring gas that plays a role in many body functions. Levels of eNO increase with airway inflammation, a symptom of asthma. Researchers have proposed using eNO as a nonin...

Eligibility Criteria

Inclusion

  • Participated in the Cincinnati Asthma Prevention Study
  • Diagnosis of asthma
  • Lives with someone that smokes at least 5 cigarettes a day

Exclusion

  • No additional neuromuscular or respiratory disorder that may interfere with safe participation in the parent study
  • Does not have electricity
  • Plans to move within 1 year of entry into the parent study

Key Trial Info

Start Date :

July 1 2006

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2008

Estimated Enrollment :

225 Patients enrolled

Trial Details

Trial ID

NCT00395096

Start Date

July 1 2006

End Date

June 1 2008

Last Update

August 9 2021

Active Locations (1)

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Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, United States, 45229-3039