Status:
COMPLETED
"VIBES"--Low Magnitude Mechanical Stimulation to Improve Bone Mineral Density
Lead Sponsor:
Hebrew SeniorLife
Collaborating Sponsors:
National Institute on Aging (NIA)
Conditions:
Osteopenia
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
The purpose of this study is to determine if daily low magnitude, high frequency whole body vibration can improve bone density in seniors.
Detailed Description
The treatment options for osteoporosis, a major health complication in the aged population, are limited to pharmacologic interventions, the majority of which are antiresorptive. Preliminary data demon...
Eligibility Criteria
Inclusion
- Men and women 60 years and over of all ethnic groups
- Weight less than 250 pounds
- Absence of terminal cancer or other illness necessitating hospice level services
- Capable of following the protocol and of understanding and providing informed consent
- Scoring less than 12 on the Short Blessed Test
Exclusion
- Immobilization of the axial or lower appendicular skeleton within the last year
- Nonambulatory (ambulation with an assistive device will be permitted)
- Malignancy other than cured thyroid cancer or skin cancer
- Hip replacement or internal fixation, total knee replacement, or lower limb fracture within the past year, or bilateral hip replacement
- Medications: glucocorticoids, suppressive doses of thyroid hormone as determined by screening TSH, anticonvulsant drugs (phenytoin, phenobarbital, carbamazepine), estrogen/testosterone replacement, selective estrogen receptor modulators (SERMs), PTH, or bisphosphonates more than 1 month in past year, calcitonin therapy within the preceding month, fluoride therapy at any time
- Paget's disease of bone, rheumatoid arthritis or other connective tissue disorders requiring systemic treatment with disease modifying drugs, or a history of Cushing's syndrome
- Fragility fracture within the past five years unless pharmacologic therapy not to be prescribed
Key Trial Info
Start Date :
February 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2012
Estimated Enrollment :
174 Patients enrolled
Trial Details
Trial ID
NCT00396994
Start Date
February 1 2007
End Date
June 1 2012
Last Update
March 20 2013
Active Locations (1)
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1
Hebrew SeniorLife, Institute for Aging Research
Boston, Massachusetts, United States, 02131