Status:
COMPLETED
Early Signs of Atherosclerosis in Obstructive Sleep Apnea: Effects of Treatment
Lead Sponsor:
University of Sao Paulo
Collaborating Sponsors:
Fundação de Amparo à Pesquisa do Estado de São Paulo
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Conditions:
Obstructive Sleep Apnea
Atherosclerosis
Eligibility:
MALE
30-60 years
Phase:
PHASE4
Brief Summary
Obstructive sleep apnea (OSA) is associated with adverse cardiovascular outcomes, including acute myocardial infarction and stroke. Atherosclerosis is an important step for these events. Recent studie...
Detailed Description
Obstructive sleep apnea (OSA) is characterized by recurrent episodes of partial or complete obstruction of the upper airway during sleep resulting in oxygen desaturation and arousals from sleep. OSA i...
Eligibility Criteria
Inclusion
- Males with recent sleep study (\<1 month) showing severe obstructive sleep apnea, defined as at least 30 events of apnea and hypopnea per hour of sleep.
Exclusion
- Age \>60 years old, body mass index (BMI) \>35 kg/m2, diabetes mellitus, hypertension, cerebrovascular, aortic, heart, and valvar heart diseases, renal failure, arrhythmias, smoking habit, and chronic use of medications, including statins.
Key Trial Info
Start Date :
January 1 2004
Trial Type :
INTERVENTIONAL
End Date :
July 1 2006
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT00400543
Start Date
January 1 2004
End Date
July 1 2006
Last Update
November 17 2006
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Heart Institute (InCor) - University of São Paulo Medical School
São Paulo, São Paulo, Brazil, 05403-904