Status:

UNKNOWN

Oxidative Stress Lowering Effect of Simvastatin and Atorvastatin.

Lead Sponsor:

Amsterdam UMC, location VUmc

Conditions:

Diabetes Mellitus

Hypertension

Eligibility:

All Genders

18-80 years

Phase:

PHASE4

Brief Summary

Background: HMG-CoA reductase inhibitors (statins) are effective lipid-lowering agents and are known to reduce cardiovascular events. Beneficial effects of statins seem to occur very early in the cour...

Detailed Description

Background HMG-CoA reductase inhibitors (statins) are effective lipid-lowering agents and are known to reduce cardiovascular events. It was initially assumed that cholesterol reduction by statins was ...

Eligibility Criteria

Inclusion

  • Diabetes mellitus
  • Hypertension

Exclusion

  • chronic kidney disease K/DOQI stage 5
  • use of statins

Key Trial Info

Start Date :

February 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2009

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT00404599

Start Date

February 1 2007

End Date

July 1 2009

Last Update

June 10 2008

Active Locations (1)

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VU University Medical Center

Amsterdam, Netherlands, 1007 MB