Status:
COMPLETED
Exercise Intervention Study for Early-Stage Breast Cancer Patients Receiving Neoadjuvant Therapy.
Lead Sponsor:
Duke University
Collaborating Sponsors:
United States Department of Defense
Conditions:
Breast Cancer
Eligibility:
FEMALE
18+ years
Phase:
PHASE1
PHASE2
Brief Summary
To determine the effects of endurance exercise training on cardiopulmonary fitness in breast cancer patients undergoing neoadjuvant chemotherapy.
Detailed Description
Given that this is the first study to explore the potential effects of exercise training on exercise capacity, tumor vascularity and response in women undergoing neoadjuvant chemotherapy for operable ...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Histologically confirmed operable primary breast cancer
- Age 18 or older
- Karnofsky performance status greater than 70
- No previous malignancy
- Absence of significant cardiac disease (left ventricular ejection fraction greater than or equal to 50%)
- No hormonal replacement therapy use within the past month
- Not pregnant
- Ability to read and understand English
- Signed written informed consent prior to beginning protocol specific procedures
- Willing to travel to DUMC to exercise three times per week
- Primary treating oncologist approval
Exclusion
Key Trial Info
Start Date :
September 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2010
Estimated Enrollment :
23 Patients enrolled
Trial Details
Trial ID
NCT00405678
Start Date
September 1 2006
End Date
September 1 2010
Last Update
July 11 2014
Active Locations (1)
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1
Duke University Medical Center
Durham, North Carolina, United States, 27710