Status:

WITHDRAWN

Trial of Telbivudine Combination Therapy vs. Continued Adefovir Monotherapy

Lead Sponsor:

Novartis Pharmaceuticals

Conditions:

Chronic Hepatitis B

Eligibility:

All Genders

18-70 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to find out if taking a combination of telbivudine and adefovir or tenofovir and telbivudine can lower the amount of Hepatitis B virus in patients that have been taking ad...

Eligibility Criteria

Inclusion

  • Documented compensated chronic hepatitis B defined by clinical history compatible with chronic hepatitis B
  • Patient is currently receiving Hepsera (adefovir dipivoxil) and has received treatment continuously for a minimum of 5 months prior to screening.
  • Other inclusion criteria may apply.

Exclusion

  • Patient is pregnant or breastfeeding
  • Patient is co-infected with hepatitis C, hepatitis D or HIV
  • Patient previously received nucleoside(tide) therapy other than adefovir
  • Patient previously received an interferon-based treatment or an investigational agent for hepatitis B in the preceding 12 months
  • Other exclusion criteria may apply.

Key Trial Info

Start Date :

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00409019

Last Update

March 9 2015

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