Status:
TERMINATED
Heliox-Powered Albuterol Therapy in the Treatment of Children Admitted With Acute Asthma Exacerbation
Lead Sponsor:
Children's Hospital Medical Center, Cincinnati
Conditions:
Status Asthmaticus
Eligibility:
All Genders
24-18 years
Phase:
PHASE2
Brief Summary
The purpose of this study is to investigate whether heliox-powered albuterol nebulizer therapy will result in reduced inpatient length of stay in children hospitalized with acute asthma exacerbations.
Detailed Description
We hypothesize that heliox-powered albuterol nebulizer therapy will result in reduced inpatient length of stay in children hospitalized with acute asthma exacerbations. Severity of asthma will be char...
Eligibility Criteria
Inclusion
- Age 2 -18 years;
- Previous history of asthma;
- Hospital admission for acute asthma exacerbation;
- Clinical asthma score greater than or equal to 3
Exclusion
- Less than 2 years old or over 18 years old;
- Known allergy or hypersensitivity to ß-agonists;
- Require mechanical ventilation (invasive or non-invasive);
- Require FiO2 \>0.4;
- Failure to obtain informed consent;
- Enrollment in another investigational drug or asthma protocol;
- Incipient respiratory failure including but limited to respiratory acidosis(pCO2\>60 torr), altered mental status and/or excessive work of breathing.
Key Trial Info
Start Date :
April 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2007
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT00410150
Start Date
April 1 2006
End Date
December 1 2007
Last Update
November 8 2010
Active Locations (1)
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1
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States, 45229