Status:

COMPLETED

Insulin Secretory Defects in Pima Indians at High Risk for NIDDM

Lead Sponsor:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Conditions:

NIDDM

Eligibility:

All Genders

18-65 years

Brief Summary

The Pima Indians have the highest reported prevalence of NIDDM of any population in the world. Within this population, it is possible to identify subgroups of individuals at a particularly high risk f...

Detailed Description

The Pima Indians have the highest reported prevalence of NIDDM of any population in the world. Within this population, it is possible to identify subgroups of individuals at a particularly high risk f...

Eligibility Criteria

Inclusion

  • INCLUSION CRITERIA:
  • Healthy men and women (Pimas and non-Pimas)
  • At least 18 years of age
  • EXCLUSION CRITERIA:
  • Pregnancy and/or breastfeeding
  • Positive urine drug screening test
  • Inability to provide informed consent
  • Medical conditions or medications that, in the investigators' judgement, would affect glucose metabolism or insulin secretion. Examples include, but are not limited to: hyper- or hypothyroidism or other endocrine disorders, cardiovascular disease by history or examination, pancreatitis, hepatitis, cirrhosis or other gastrointestinal disease, renal insufficiency, active alcoholism or other substance abuse problems.

Exclusion

    Key Trial Info

    Start Date :

    August 19 1996

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    August 16 2011

    Estimated Enrollment :

    310 Patients enrolled

    Trial Details

    Trial ID

    NCT00410800

    Start Date

    August 19 1996

    End Date

    August 16 2011

    Last Update

    July 2 2017

    Active Locations (1)

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    NIDDK, Phoenix

    Phoenix, Arizona, United States, 85014