Status:
COMPLETED
Programmed Intermittent Epidural Bolus Time Interval and Injection Volume
Lead Sponsor:
Northwestern University
Conditions:
Labor Pain
Eligibility:
FEMALE
18-45 years
Phase:
NA
Brief Summary
Studies suggest that administration of maintenance epidural solutions as programmed or automated intermittent boluses, rather than continuous infusions, result in lower bupivacaine consumption, decrea...
Detailed Description
Traditionally, neuraxial labor analgesia was maintained for the duration of labor with manual intermittent bolus injection of anesthetic by the anesthesiologist via an in-dwelling epidural catheter. D...
Eligibility Criteria
Inclusion
- Healthy
- nulliparous women
- term gestation (greater than or equal to 37 weeks gestation)
- spontaneous labor or with spontaneous rupture of membranes
Exclusion
- Systemic disease (e.g., diabetes mellitus, hypertension, preeclampsia)
- use of chronic analgesic medications
- systemic opioid labor analgesia prior to the initiation of neuraxial labor analgesia
- cervical dilation less than 2cm or greater than 5cm at time of initiation of neuraxial analgesia
- delivery within 90 minutes of intrathecal injection
Key Trial Info
Start Date :
August 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2009
Estimated Enrollment :
190 Patients enrolled
Trial Details
Trial ID
NCT00417027
Start Date
August 1 2006
End Date
April 1 2009
Last Update
April 14 2014
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Northwestern Memorial Hospital
Chicago, Illinois, United States, 60611