Status:
COMPLETED
A Follow-up, Family Study on Attention-deficit Hyperactivity Disorder
Lead Sponsor:
National Taiwan University Hospital
Collaborating Sponsors:
National Health Research Institutes, Taiwan
Conditions:
Attention Deficit Hyperactivity Disorder
Eligibility:
All Genders
10-18 years
Brief Summary
Background: Attention deficit hyperactivity disorder (ADHD), characterized by inattention, hyperactivity and impulsivity, is an early onset, common (5-10% worldwide; 7.5% in Taiwan), clinically hetero...
Detailed Description
(A) Specific Aims The ultimate goals of this family study are to identify the endophenotypes that are closer to the biological expression of genes underlying ADHD, to identify patterns of familial ag...
Eligibility Criteria
Inclusion
- Community-based sample for the development of several Chinese versions of instruments: SNAP-IV, SDQ, ASRI, and ASRS.
- ADHD follow-up family studies (ADHD group): (1) that subjects either had the clinical diagnosis of DSM-IV ADHD, which was made by a full-time child psychiatrist at the first visit and following visits or by a child psychiatrist using the K-SADS-E as the second-stage case ascertainment at an epidemiological study; (2) the diagnoses of ADHD were made 3-6 years ago; (3) their ages range from 12 to 15 when we conduct study; (4) subjects have at least one sibling aged 6-18 and live with at least one biological parent; and (5) subjects and their family consent to participate in this study.
- (control group)(1) that subjects were assessed either at a clinical setting or in an epidemiological study same as to those in the exposed group 6 years ago; (2) their ages range from 12 to 15 when we conduct study; (3) subjects have at least one sibling aged 6-18 and live with at least one biological parent; and (4) subjects and their family consent to participate in this study.
Exclusion
- The subjects, including those who in the exposed and unexposed groups, will be excluded from the study if they currently meet criteria or have a history of the following condition as defined by DSM-IV: Schizophrenia, Schizoaffective Disorder, Organic Psychosis, Mental Retardation, or Pervasive Developmental Disorder. Moreover, the subjects will be excluded from the unexposed group if have a history of the following condition as defined by DSM-IV: ADHD, ODD, or CD in addition to the above exclusion criteria.
Key Trial Info
Start Date :
January 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2009
Estimated Enrollment :
1800 Patients enrolled
Trial Details
Trial ID
NCT00417781
Start Date
January 1 2005
End Date
December 1 2009
Last Update
November 14 2012
Active Locations (1)
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1
National Taiwan Univeristy Hospital
Taipei, Taiwan, 10002