Status:

COMPLETED

Open-label, Pharmacokinetic, Safety and Efficacy Study of Adjunctive Brivaracetam in Children With Epilepsy.

Lead Sponsor:

UCB Pharma

Conditions:

Epilepsy

Eligibility:

All Genders

1-16 years

Phase:

PHASE2

Brief Summary

Initial study in children with epilepsy to evaluate the pharmacokinetics, safety, tolerability and preliminary efficacy of adjunctive treatment with brivaracetam, and to develop dosing adaptations for...

Eligibility Criteria

Inclusion

  • Clinical diagnosis of epilepsy
  • Subject having at least 1 seizure (any type) during the 3 weeks before first visit
  • Stable dosing of 1-3 concomitant antiepileptic drugs

Exclusion

  • Pregnant or nursing females
  • Concomitant use of Levetiracetam
  • Epilepsy secondary to a Progressive cerebral disease/tumor or other neurodegenerative disease
  • History of status epilepticus
  • Clinically significant acute or chronic illness, underlying disease or medication condition
  • History of suicide attempt

Key Trial Info

Start Date :

July 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2013

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT00422422

Start Date

July 1 2011

End Date

March 1 2013

Last Update

July 11 2018

Active Locations (39)

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Page 1 of 10 (39 locations)

1

108

Gulf Breeze, Florida, United States

2

110

Miami, Florida, United States

3

103

Wellington, Florida, United States

4

106

Boston, Massachusetts, United States