Status:

COMPLETED

Genetic Study of Patients Suffering From Congenital Amaurosis of Leber or From an Early Severe Retinal Dystrophy

Lead Sponsor:

Nantes University Hospital

Conditions:

Amaurosis

Retinal Diseases

Eligibility:

All Genders

Phase:

NA

Brief Summary

Retinal dystrophies are responsible for numerous cases of blindness, and there are no therapeutic possibilities today. Gene therapy is efficient in a dog model concerning dystrophy linked to a mutatio...

Eligibility Criteria

Inclusion

  • Patients with clinical characteristics of amaurosis of Leber
  • Patients suffering from an early severe retinal dystrophy
  • Patients with social insurance
  • Patients with a consent form signed

Exclusion

  • Retinal dystrophy with autosomal dominant transmission
  • Retinal dystrophy occuring after 5 years of age
  • Syndromical retinal dystrophy with one or more systemic manifestations
  • Familial macular degeneration
  • Familial choroid dystrophy
  • Non-degenerative retinopathology

Key Trial Info

Start Date :

April 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

Estimated Enrollment :

360 Patients enrolled

Trial Details

Trial ID

NCT00422721

Start Date

April 1 2007

Last Update

November 24 2011

Active Locations (1)

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Page 1 of 1 (1 locations)

1

CHU de Nantes

Nantes, France, 44093