Status:
TERMINATED
Efficacy Study of Homeopathic Potassium Dichromate to Treat Tracheal Secretions in Critically Ill Patients
Lead Sponsor:
Sunnybrook Health Sciences Centre
Conditions:
Ventilator Adverse Event
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
The purpose of this study is to find out whether homeopathic potassium dichromate will decrease the time on the breathing machine and the amount of phlegm that you produce in your lungs. In addition, ...
Detailed Description
Prolonged mechanical ventilation is associated with greater mortality, increased need for tracheostomy, prolonged length of critical care stay and higher costs. Risk factors identifying patients at gr...
Eligibility Criteria
Inclusion
- Patients 18yrs and older
- Situated in the Critical Care areas of Sunnybrook Health Sciences Centre including the Critical Care Unit, Cardiovascular Surgery Intensive Care Unit, Ross Tilley Burn Centre and B5/D4 intensive care units.
- They will have been weaned from mechanical ventilation (eg: extubated, face mask or tracheostomy mask, minimal pressure support or CPAP, FiO2 \<0.3) but are unable to be transferred out of the unit due to excessive and/or persistent secretions for at least 48 hours.
- Persistent secretions will be defined as suctioning of greater than every 2 hours or a score of greater than 20-24 "MP" per day. (In the Critical Care areas, each time a patient is suctioned, secretions are quantified on a scale of 1-3, with "MP" being mucopurulent in nature).
Exclusion
- Those with evidence of untreated respiratory infections or infections treated for less than 48 hours.
- Those patients on high dose steroids as defined by greater than:Fluticasone 125ug inhaler- four puffs twice daily and/or Prednisone 20mg daily orally
- Patients with multiple drug and/or environmental allergies
- Those patients who fail to give informed written consent.
- Those patients currently enrolled in another clinical trial or who have been approached for participation in a trial during the last 30 days.
- Previous enrollment in this study
- Pregnancy- all women of child bearing age will be administered a pregnancy test before inclusion into the study to verify their status.
Key Trial Info
Start Date :
January 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2010
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT00425633
Start Date
January 1 2007
End Date
January 1 2010
Last Update
March 25 2011
Active Locations (1)
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1
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada, M4N 3M5