Status:

COMPLETED

Understanding Pine Bark Extract as an Alternative Treatment (UPBEAT) Study

Lead Sponsor:

Stanford University

Collaborating Sponsors:

Funded by Toyo Shinyaku Co Ltd

Conditions:

Hypertension

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to investigate the efficacy of Flavangenol® (Toyo Shinyaku, Japan), a pine bark extract, in lowering blood pressure and improving glycemic control and plasma lipoprotein p...

Detailed Description

Cardiovascular disease is the number one cause of death in the Unites States. Our study tests the efficacy of pine bark extract in improving a number of cardiovascular disease risk factors. We are con...

Eligibility Criteria

Inclusion

  • Systolic blood pressure between 125 and 159 mmHg and diastolic blood pressure (DBP) \< 100 mmHg
  • Body mass index (BMI) 25.0-34.9
  • Triglycerides (TG) \< 450 mg/dL
  • Low Density Lipoprotein (LDL) \< 200 mg/dL
  • Fasting blood glucose (FBG) \< 126 mg/dL

Exclusion

  • DBP \> 95 mmHg
  • LDL \> 170 mg/dL
  • TG \> 300 mg/dL
  • FBG \> 110 mg/dL

Key Trial Info

Start Date :

October 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2008

Estimated Enrollment :

130 Patients enrolled

Trial Details

Trial ID

NCT00425945

Start Date

October 1 2006

End Date

August 1 2008

Last Update

April 2 2014

Active Locations (1)

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Stanford University School of Medicine

Stanford, California, United States, 94305