Status:
RECRUITING
Physical and Behavioral Traits of Overweight and Obese Adults
Lead Sponsor:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Obesity
Healthy Volunteers
Eligibility:
All Genders
18-100 years
Brief Summary
This study will describe the phenotype (physical and behavioral traits) of overweight and obese people. It will characterize the hormones, metabolism, food preferences, fitness and physical activity l...
Detailed Description
Although complex metabolic, hormonal, and neural networks operate to control body weight, obesity is in most cases, the result of over-feeding and inactivity. In most obese patients, patterns of funda...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Obese subjects:
- Obese men and women over the age of 18 years
- BMI \> 30
- Overweight subjects:
- Overweight men and women over the age of 18 years
- BMI \> 25 and \< 30
- Control subjects (may be matched for age, sex and years of education):
- Normal weight men and women over the age of 18 years
- BMI \> 18.5 and \< 25
- EXCLUSION CRITERIA:
- Patients with significant physical limitations that may preclude them from completing the majority of the tests in this study
- Current unstable medical conditions including cardiac ischemia, severe respiratory insufficiency requiring oxygen therapy, hepatic or cardiac failure as assessed by history and physical exam
- Any psychiatric condition that would preclude participation in the study
- Patients unwilling or unable to give informed consent
- Pregnant woman.
- Additional exclusion for lean control subjects:
- Previous history of obesity as an adolescent or adult
- Current or past history of eating disorders such as anorexia nervosa or bulimia
- The NIH Patient Recruitment and Public Liaison Office will receive inquiries from interested study subjects. Pre-screening by this office will exclude patients who require more than minimal assistance to complete activities of daily living in order to select subjects who can safely participate in the full phenotyping protocol. All others will be contacted by the protocol team to review exclusion criteria. Eligible patients will be invited to Clinical Research Center for a screening visit.
Exclusion
Key Trial Info
Start Date :
March 8 2007
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
2000 Patients enrolled
Trial Details
Trial ID
NCT00428987
Start Date
March 8 2007
Last Update
January 8 2026
Active Locations (1)
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1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892