Status:
WITHDRAWN
Trial of 2nd Generation Anti-CEA Designer T Cells in Gastric Cancer
Lead Sponsor:
Roger Williams Medical Center
Conditions:
Gastric Cancer
Eligibility:
All Genders
18+ years
Phase:
PHASE1
Brief Summary
This study proposes to determine the safety and tolerability of 2nd generation designer T cells in patients with gastric cancer.Designer T cells are prepared by removing white blood cells from the par...
Detailed Description
T cells can penetrate virtually every biologic space and have the power to dispose of normal or malignant cells as seen in viral and autoimmune diseases and in the rare spontaneous remissions of cance...
Eligibility Criteria
Inclusion
- CEA expressing Gastric Cancer/GE Junction (\>10ng/ml)
- Must have measurable disease radiologically or by physical exam
- Must have failed potentially curative standard therapy
- Must be 18 years of age or older
- No serious concomitant disease
Exclusion
- Prior investigational treatment
- Requiring systemic steroids
- Serious medical conditions
- Concurrent malignancies
Key Trial Info
Start Date :
July 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2011
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00429078
Start Date
July 1 2007
End Date
April 1 2011
Last Update
March 2 2012
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