Status:
COMPLETED
A RCT of Ondansetron and Promethazine in the Treatment of Nausea and Vomiting in the Emergency Department
Lead Sponsor:
University of New Mexico
Collaborating Sponsors:
GlaxoSmithKline
Conditions:
Nausea
Vomiting
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
This was a trial comparing two commonly used medications for nausea and vomiting, ondansetron and promethazine, in the Emergency Department.
Detailed Description
Nausea and vomiting are common complaints in the emergency department (ED). There are many pharmacologic agents used for the treatment of these complaints. None are new nor experimental. Very little r...
Eligibility Criteria
Inclusion
- Age 18 or older
- Chief complaint of nausea or vomiting
Exclusion
- Age less than 18
- unable to provide informed consent
- rate nausea at \< 40 mm on 100 mm VAS
- received antiemetic within 24 hours
- pregnant or possibly pregnant
- reported allergy to either study medication
- received more than 1 liter of intravenous fluids
- their primary ED physician declined to have patient participate
Key Trial Info
Start Date :
October 1 2003
Trial Type :
INTERVENTIONAL
End Date :
November 1 2005
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00429832
Start Date
October 1 2003
End Date
November 1 2005
Last Update
February 1 2007
Active Locations (1)
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1
University of New Mexico Hospital Emergency Department
Albuquerque, New Mexico, United States, 87131