Status:
COMPLETED
Combination Chemotherapy Based on Risk of Relapse in Treating Young Patients With Acute Lymphoblastic Leukemia
Lead Sponsor:
University Hospital Schleswig-Holstein
Conditions:
Leukemia
Eligibility:
All Genders
1-18 years
Phase:
PHASE3
Brief Summary
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination c...
Detailed Description
OBJECTIVES: * Compare the relative efficacy of induction therapy comprising dexamethasone or prednisone, in terms of a higher rate of event-free survival (EFS) and overall survival and a reduced rate...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Histologically confirmed acute lymphoblastic leukemia (ALL)
- No secondary ALL
- PATIENT CHARACTERISTICS:
- No prior disease that would preclude treatment with chemotherapy
- PRIOR CONCURRENT THERAPY:
- More than 4 weeks since prior chemotherapy
- More than 4 weeks since prior steroids
Exclusion
Key Trial Info
Start Date :
July 1 2000
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2012
Estimated Enrollment :
4559 Patients enrolled
Trial Details
Trial ID
NCT00430118
Start Date
July 1 2000
End Date
January 1 2012
Last Update
May 29 2013
Active Locations (76)
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1
Krankenhaus Dornbirn
Dornbirn, Austria, A-6850
2
Landeskrankenhaus Feldkirch
Feldkirch-Tisis, Austria, A-6807
3
Universitaet Kinderklinik
Graz, Austria, 8036
4
Innsbruck Universitaetsklinik
Innsbruck, Austria, A-6020