Status:
ACTIVE_NOT_RECRUITING
Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus
Lead Sponsor:
Johns Hopkins University
Collaborating Sponsors:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Cancer Institute (NCI)
Conditions:
Barrett Esophagus
Esophageal Neoplasm
Eligibility:
All Genders
18-95 years
Brief Summary
The purpose of this study is to determine if there are any early changes in DNA markers of blood and esophageal tissue in people with gastric reflux, Barrett's esophagus or esophageal cancer that can ...
Detailed Description
Patients with Barrett's esophagus (BE) have an increased risk of esophageal adenocarcinoma which is 40-125 fold higher than in the general population. However, the current techniques of detecting dysp...
Eligibility Criteria
Inclusion
- People who are undergoing upper endoscopy as part of their medical care with a history of esophageal cancer, Barrett's esophagus, or upper gastrointestinal symptoms.
Exclusion
- People who are are currently having chemotherapy, or who have completed chemotherapy within the last 4 weeks.
- People who have ever had radiation treatments to their chest.
Key Trial Info
Start Date :
May 1 2002
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2026
Estimated Enrollment :
600 Patients enrolled
Trial Details
Trial ID
NCT00431756
Start Date
May 1 2002
End Date
June 1 2026
Last Update
December 16 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Johns Hopkins Hospital
Baltimore, Maryland, United States, 21287