Status:
TERMINATED
Steady State Serum and Epithelial Lining Fluid (ELF) Antibiotics Concentrations Under Continous Infusion
Lead Sponsor:
University Hospital Tuebingen
Conditions:
Pneumonia
Bacteremia
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of our study is to determine the penetration of continuously infused antibiotics at steady state, mainly Meropenem, Vancomycin, Linezolid, Piperacillin/tazobactam and additionally cefepim ...
Detailed Description
Severe infectious disease may be the cause for admitting a patient to an ICU, but more often they constitute a complication of the intensive care and turn out to be caused by nosocomial pathogens. No...
Eligibility Criteria
Inclusion
- Patients of both gender \>0 18 years of age
- Patients of an ICU with one or more of the following infections
- Bacteremia. sepsis
- pneumonia
- tracheo-bronchitis
- mechanical ventilation
- stay on the ICU \>= 3 days
- indication for bronchoscopy
Exclusion
- pregnancy
- allergy against the studied drug
- known resistance of the involved pathogen against the study drug
- simultaneous participation in other studies
- former participation in the present study
- probable stay on the ICU \< 3 days
- contra-indication against the study-drug
- contra-indication for bronchoscopy
Key Trial Info
Start Date :
November 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 1 2007
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00435305
Start Date
November 1 2006
End Date
November 1 2007
Last Update
June 9 2008
Active Locations (1)
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1
Universitäsklinikum Tübingen, Klinik für Anästhesiologie und Intensivmedizin
Tübingen, Germany, 72076