Status:
COMPLETED
Leeches for the Treatment of Knee Osteoarthritis
Lead Sponsor:
RWTH Aachen University
Collaborating Sponsors:
University Hospital, Aachen
Conditions:
Osteoarthritis
Arthralgia
Eligibility:
All Genders
Phase:
PHASE2
Brief Summary
Previous studies have not addressed the question, whether or not a repeated leeching can supply symptomatic relief of osteoarthritic pain for extended periods of time. We present a randomized study to...
Eligibility Criteria
Inclusion
- Osteoarthritis of the knee
- Persistent osteoarthritic symptoms for at least 6 months
- Radiographic evidence of late stage osteoarthritis of the knee (stage III-IV)
- History of conservative management including pain medication and physical therapy
Exclusion
- Anticoagulant treatment or history of hemophilia
- History or presence of rheumatic diseases leading to secondary osteoarthritis
- Presence of hematological, hepatic, renal or immunological disease
- Insulin-dependant diabetes mellitus
- Intraarticular injections or systemic application of corticosteroids during the 3 preceding months
- History of surgery of the affected knee during the last 3 months or joint replacement
- History of previous leech therapy
- Lack of informed consent
Key Trial Info
Start Date :
February 1 2004
Trial Type :
INTERVENTIONAL
End Date :
December 1 2004
Estimated Enrollment :
118 Patients enrolled
Trial Details
Trial ID
NCT00435773
Start Date
February 1 2004
End Date
December 1 2004
Last Update
April 9 2007
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Orthopaedic Surgery, University Hospital of the RWTH Aachen, Germany
Aachen, Germany, 52074