Status:
COMPLETED
Cancer of the Pancreas Screening Study (CAPS 3)
Lead Sponsor:
Johns Hopkins University
Collaborating Sponsors:
Lustgarten Foundation
National Cancer Institute (NCI)
Conditions:
Pancreatic Neoplasm
Peutz-Jeghers Syndrome
Eligibility:
All Genders
40-80 years
Brief Summary
The purpose of this study is to find the best and most sensitive screening modality (CT, MRI, EUS)for very small pre-cancerous pancreatic lesions and to treat these small lesions before they turn into...
Detailed Description
Pancreatic cancer (PC) is the 4th leading cause of cancer death in the U.S. Because it is seldom diagnosed at an early curable stage, nearly all patients die from their disease. Early detection of PC ...
Eligibility Criteria
Inclusion
- Persons with a verified family history of 2 or more first degree relatives with primary site pancreatic cancer(PC), age 40-80 years old or if 1 first degree relative also has at least 2 second degree relatives affected with PC.
- Persons with a verified BRCA2 gene mutation or FAMM/p16 gene mutation, age 40-80 years old, and family history of pancreatic cancer.
- Persons with Peutz-Jeghers Syndrome, 30-80 years old, and family history of pancreatic cancer.
Exclusion
- Persons with pancreatic cancer, or suspicious symptoms.
- Persons who have had pancreas specific imaging protocol performed in the past three years.
- Persons medically unable to have an endoscopy, CT or MRI procedure
Key Trial Info
Start Date :
December 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2009
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT00438906
Start Date
December 1 2006
End Date
December 1 2009
Last Update
June 18 2021
Active Locations (1)
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1
Johns Hopkins Hospital
Baltimore, Maryland, United States, 21287