Status:
COMPLETED
Acceptance Therapy During Methadone Detoxification
Lead Sponsor:
The University of Texas Health Science Center, Houston
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
Opiate Dependence
Eligibility:
All Genders
25-60 years
Phase:
PHASE1
Brief Summary
The purpose of this study is to develop an opiate detoxification behavior therapy based on current Acceptance and Commitment Therapy (ACT) theory and method, and to test its feasibility and promise in...
Detailed Description
This Stage I pilot study will employ a randomized, controlled, between groups design in which 70 opiate dependent patients seeking methadone detoxification will be randomized into one of two treatment...
Eligibility Criteria
Inclusion
- Ages 25 through 60
- Dependent upon opiates (heroin/methadone) according to DSM-IV criteria
- Using heroin/methadone for at least 5 years
- Endorse 7 or higher on a 10-point motivation for opiate detoxification item
- In good physical and psychiatric health
- Able to read, speak, and understand English
- Willing and able to meet study requirements
- Willing to participate in the 1 month follow up session
- Able to provide the name of at least one person who can generally locate them
- Attending a licensed methadone clinic regularly with opiate (other than methadone) negative urine screens in the past month.
- Intake screen negative for opiates (other than methadone)
- \>110 lbs \& body mass index between 18 and 28 kg/m2
Exclusion
- Younger than 25 and older than 60 years of age
- Current dependence on other substances
- Severe medical, cognitive, and/or psychiatric impairment that precludes cooperation with study protocol
- Current and severe psychiatric symptoms requiring medical attention
- Current substance withdrawal symptoms requiring medical attention
- Unable to read, speak, and understand English
- Unwillingness of women of child bearing age to use contraception
- Currently receiving other psychosocial therapy for substance abuse (12-step meetings are ok)
- Impending incarceration
- Unable or unwilling to meet study requirements, including provision of signed consent
- Less than 7 on a 10-point motivation for opiate detoxification scale
- no documentation of monitored methadone use
- non-methadone opiate positive urine screen in the past month according to self-report
Key Trial Info
Start Date :
July 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
56 Patients enrolled
Trial Details
Trial ID
NCT00439036
Start Date
July 1 2006
End Date
December 1 2012
Last Update
May 6 2013
Active Locations (1)
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1
University of Texas Medical School- Houston; Department of Psychiatry; Mental Sciences Institute
Houston, Texas, United States, 77030