Status:

COMPLETED

Exploration of the Synovial Fluid Inflammation Mediators Under Diacerhein in Knee Osteoarthritis

Lead Sponsor:

Laboratoires NEGMA

Conditions:

Osteoarthritis

Eligibility:

All Genders

45-80 years

Phase:

PHASE4

Brief Summary

Some inflammation mediators, notably IL-1, are implied in the joint degeneration phenomena of osteoarthritis. The aim of this study is to confirm in vivo the favourable effect of diacerhein on IL-1 an...

Eligibility Criteria

Inclusion

  • Painful osteoarthritis
  • Hydarthrosis (synovial effusion)

Exclusion

  • large effusion
  • severe pathologies
  • anti-osteoarthritic treatments

Key Trial Info

Start Date :

March 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2008

Estimated Enrollment :

96 Patients enrolled

Trial Details

Trial ID

NCT00440661

Start Date

March 1 2007

End Date

October 1 2008

Last Update

March 4 2010

Active Locations (1)

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1

Rheumatologic Institut of Montreal

Montreal, Quebec, Canada, H2L1S6