Status:

COMPLETED

An Extension Trial to a Phase I Dose Escalation Study of Gimatecan Administered Orally 5 Consecutive Days to Japanese Patients With Advanced Solid Tumor

Lead Sponsor:

Novartis Pharmaceuticals

Conditions:

Advanced Solid Tumors

Eligibility:

All Genders

20+ years

Phase:

PHASE1

Brief Summary

CLBQ707A1101 assesses the tolerability, safety, efficacy and pharmacokinetics of gimatecan in Japanese patients.

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Patients completing the core protocol (CLBQ707A1101, NCT00410358) exhibiting stable disease, or a partial or complete response as defined by the core protocol. If patients only have non-measurable lesions, he/she must not be exhibiting progressive disease
  • Exclusion criteria:
  • Documented progressive disease as defined by the core protocol
  • Patients with performance status of 3 or 4 on the ECOG scale
  • Other protocol-defined inclusion/exclusion criteria may apply

Exclusion

    Key Trial Info

    Start Date :

    January 1 2007

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    Estimated Enrollment :

    4 Patients enrolled

    Trial Details

    Trial ID

    NCT00441610

    Start Date

    January 1 2007

    Last Update

    December 19 2020

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Novartis Investigative Site

    Chiba, Japan