Status:

WITHDRAWN

"The Evaluation of Stimulant Withdrawal"

Lead Sponsor:

Aaron J. Janowsky

Collaborating Sponsors:

National Institute on Drug Abuse (NIDA)

Conditions:

Anxiety

Relapse

Eligibility:

All Genders

18-65 years

Phase:

PHASE2

Brief Summary

The purpose of this research study is to determine whether Carvedilol, an FDA approved beta blocker, when administered for an 8-week period to veterans currently undergoing treatment for methamphetami...

Eligibility Criteria

Inclusion

  • Must have entered treatment into the outpatient Clinical Addiction Rehabilitation Section (CARS) through the US Portland Veterans Affairs Medical Center
  • Must meet the clinical definition for methamphetamine dependence
  • Self-reported methamphetamine use within 10 days of entering the study
  • Must be able to understand and sign the consent form

Exclusion

  • Dependent on any other drug except nicotine, caffeine, marijuana and alcohol
  • Pregnant or nursing mothers
  • Psychosis
  • Dementia
  • Any serious medical condition that could be aggravated by the study protocol (Allergic reaction, Hypotension, Asthma, Bronchospastic conditions, Angina, Bronchitis, Emphysema, Bradycardia, Heart or blood vessel disease, Diabetes mellitus, Low blood sugar, Kidney disease, Liver disease or Overactive thyroid)
  • History of withdrawal seizures or delirium tremors
  • Use of MAO inhibitors within the last two weeks
  • Considerable hepatocellular injury, including cirrhosis of the liver or liver function test levels higher than 2 times normal

Key Trial Info

Start Date :

July 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 30 2011

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00442923

Start Date

July 1 2007

End Date

June 30 2011

Last Update

January 31 2019

Active Locations (1)

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1

US Veterans Hospital

Portland, Oregon, United States, 97239