Status:
COMPLETED
Effects of Ghrelin on the Sleep-EEG and Nocturnal Secretion of Hormones
Lead Sponsor:
Max-Planck-Institute of Psychiatry
Collaborating Sponsors:
German Research Foundation
Conditions:
Healthy
Major Depression
Eligibility:
All Genders
20-70 years
Phase:
NA
Brief Summary
Ghrelin, an acylated peptide consisting of 28 amino acids, is the endogenous ligand of the growth hormone secretagogue receptor (GHS-R). It is synthesized predominantly in the stomach but has been als...
Eligibility Criteria
Inclusion
- Healthy females and males
- Male and female patients with major depression
Exclusion
- Life time or family history of psychiatric or neurological disorders
- Sleep disturbances
- Shift work
- Any current disease
- Any medication
- Long distance flight within 3 months prior to study entry
- Smoking
- Any medication during the week prior to study entry
- Any current disease other than major depression
Key Trial Info
Start Date :
March 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2007
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT00447512
Start Date
March 1 2004
End Date
October 1 2007
Last Update
October 31 2007
Active Locations (1)
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1
Max Planck Institute of Psychiatry
Munich, Germany, 80804