Status:
COMPLETED
Viral Infections in Chronic Obstructive Pulmonary Disease (COPD) Exacerbations
Lead Sponsor:
University Hospital, Geneva
Collaborating Sponsors:
Ligue Pulmonaire Genevoise
Conditions:
Pulmonary Disease, Chronic Obstructive
Respiratory Tract Infections
Eligibility:
All Genders
18+ years
Brief Summary
The objectives of the study are * to determine the prevalence of respiratory virus infections in COPD patients, during and outside acute exacerbation * to explore the impact of these viral infections...
Detailed Description
Background Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity due to repeated exacerbations. The impact of viral infections during and outside COPD exacerbations is poorly u...
Eligibility Criteria
Inclusion
- All consecutive patients known or suspected for moderate to very severe COPD and admitted in the emergency center for an acute exacerbation of their COPD
- Age above 18 years
- We plan to include 100 patients with a complete work-up and follow-up
- Written informed consent will be obtained from every participant
Exclusion
- Patients requiring oro-tracheal intubation
- Patients unable to give their informed consent due to their clinical condition
- Other obvious cause of dyspnea (pulmonary embolism, acute pulmonary edema, lobar pneumonia)
- Patients suffering from bronchiectasis, asthma, pulmonary fibrosis and mineral dust pneumoconiosis
- Patients with a history of active tuberculosis
- Patients with a history of ischemic cerebral stroke and subsequent deglutition dysfunction
Key Trial Info
Start Date :
May 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2009
Estimated Enrollment :
86 Patients enrolled
Trial Details
Trial ID
NCT00448604
Start Date
May 1 2007
End Date
September 1 2009
Last Update
November 4 2010
Active Locations (1)
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1
Geneva University Hospital
Geneva, Canton of Geneva, Switzerland, 1211