Status:
COMPLETED
Quinolone Resistance in Bloodstream Isolates of Escherichia Coli
Lead Sponsor:
University of Pittsburgh
Conditions:
Bacterial Infections
Eligibility:
All Genders
18+ years
Brief Summary
This proposed study aims to document the risk factors for quinolone resistance in bloodstream isolates of E. coli. Additionally, the adequacy of empiric antibiotic therapy for E. coli bloodstream infe...
Detailed Description
The following information will be collected: age, sex, occupation, hospital location at the time of positive culture (ER, medical ward, ICU etc), date of positive culture, prior hospitalization, recei...
Eligibility Criteria
Inclusion
- Clinical information is collected by chart review of "case" and "control" patients.
- A "case A" patient is defined as follows:
- One or more blood cultures are positive for E. coli. The organism is ciprofloxacin resistant.
- A "case B" patient is defined as follows:
- One or more blood cultures are positive for E. coli. The organism is ciprofloxacin susceptible. Additionally, 4 controls who are in hospital at the same time as cases will be selected for each case.
Exclusion
- If they do not meet inclusion criteria
Key Trial Info
Start Date :
March 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2017
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT00449735
Start Date
March 1 2007
End Date
June 1 2017
Last Update
June 12 2018
Active Locations (1)
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1
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States, 15213