Status:
COMPLETED
Risk Stratification of Non ST Elevation ACS With Computed Tomographic Angiography (REACT)
Lead Sponsor:
Ottawa Heart Institute Research Corporation
Conditions:
Acute Coronary Syndrome
Non-ST-Elevation Myocardial Infarction
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this project is to examine the effectiveness of computed tomographic angiography (CTA) in patients with non-ST elevation acute coronary syndrome (NSTE-ACS). People who are hospitalized ...
Eligibility Criteria
Inclusion
- High risk ACS
- Angina \[accelerating pattern or prolonged episode (\> 20 minutes) or recurrent episode at rest or with minimal effort within preceding 24 hours\]; and (13)
- Elevated Troponin - T (≥0.1 ug/L) or ECG changes consistent with ischemia \[ST depression ≥ 0.1 mV, transient ST segment elevation ≥ 0.1 mV (\< 20 minutes)\]) (11;13)
- Planned conventional invasive coronary angiography
Exclusion
- Age \< 18 years or lack of consent
- Renal Insufficiency (GFR \< 60 ml/min)
- Allergy to contrast agent
- Refractory angina requiring urgent/emergent coronary angiography (as per treating physician)
- Contraindication to radiation exposure (e.g. pregnancy)
- Uncontrolled HR
- Previous CABG or PCI/Stent
- Atrial fibrillation, frequent atrial or ventricular ectopy (\> 1 / minute)
- Unable to perform 20 second breath-hold
Key Trial Info
Start Date :
September 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2010
Estimated Enrollment :
107 Patients enrolled
Trial Details
Trial ID
NCT00449826
Start Date
September 1 2006
End Date
December 1 2010
Last Update
January 26 2012
Active Locations (1)
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1
University of Ottawa Heart Institute
Ottawa, Ontario, Canada, K1Y 4W7