Status:
UNKNOWN
Identifying Gene Mutations in Patients With Melanoma and in Families With a History of Hereditary Melanoma
Lead Sponsor:
Leeds Cancer Centre at St. James's University Hospital
Conditions:
Hereditary Multiple Melanoma
Melanoma (Skin)
Eligibility:
All Genders
Brief Summary
RATIONALE: Identifying gene mutations and other risk factors in patients with melanoma and in families with a history of hereditary melanoma may help doctors identify persons at risk for melanoma and ...
Detailed Description
OBJECTIVES: * Determine the incidence and etiologic significance of variants of known melanoma susceptibility genes (MSGs) in families with multiple cases of melanoma. * Determine the proportion of m...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Meets one of the following criteria:
- Prior multiple primary melanomas
- Histological samples available
- Family history of melanoma, with melanoma in two first-degree relatives (e.g., cases of melanoma in both a mother and son or in two brothers but not in two cousins)
- Family history of melanoma, where three or more individuals (of any relationship) have had melanoma
- PATIENT CHARACTERISTICS:
- Not specified
- PRIOR CONCURRENT THERAPY:
- Not specified
Exclusion
Key Trial Info
Start Date :
January 1 1989
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
5000 Patients enrolled
Trial Details
Trial ID
NCT00450593
Start Date
January 1 1989
Last Update
August 12 2013
Active Locations (1)
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1
Leeds Cancer Centre at St. James's University Hospital
Leeds, England, United Kingdom, LS9 7TF