Status:
UNKNOWN
Statin for Immunomudulation in Sepsis
Lead Sponsor:
Hospital de Clinicas de Porto Alegre
Conditions:
Sepsis
Eligibility:
All Genders
15+ years
Phase:
PHASE2
Brief Summary
The purpose of this study is to determine whether atorvastatin can improve the inflammatory answer in the septic patients
Eligibility Criteria
Inclusion
- clinical diagnosis of several sepsis or shock septic
- no more than twenty four hours than diagnosis
Exclusion
- use of statins in the last thirty days
- unequivocal indication for statin treatment
- active treatment with imunosuppressors drugs
- High risk of rhabdomyolysis: multiple trauma, crush injuries, baseline creatinine kinase \> three times upper limit of normal
- diagnosis of AIDS
- unable to receive enteral medications
- pregnancy
- expected survival of less than 48 hours
Key Trial Info
Start Date :
December 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2009
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT00452608
Start Date
December 1 2006
End Date
December 1 2009
Last Update
June 26 2009
Active Locations (1)
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1
HCPA - Clinical Hospital fo Porto Alegre
Porto Alegre, Rio Grande do Sul, Brazil, 90035-903