Status:
TERMINATED
BNP Therapy Observation Unit Outcomes STudy (BOOST)
Lead Sponsor:
Emory University
Collaborating Sponsors:
Scios, Inc.
Conditions:
Congestive Heart Failure
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The investigators hypothesize that patients admitted to an emergency department (ED) observation unit will have a decreased rate of hospital admissions and ED recidivism when treated with nesiritide v...
Detailed Description
Congestive heart failure (CHF) is a growing problem in the United States. The increasing number of decompensated heart failure patients presenting to emergency departments (ED) for treatment is worsen...
Eligibility Criteria
Inclusion
- Adult patient \> 18 years of age
- Have a working diagnosis of HF, as determined by the emergency physician using the Boston Criteria. A score of 8-12 is required for inclusion in the study.
- Alert, oriented and able to provide informed consent.
- Able to be contacted by telephone for follow up after discharge, and have none of the study exclusion criteria.
Exclusion
- Dialysis Dependent Renal Failure
- Temperature \> 38.5 degrees celsius
- Pneumonia (Infiltrates on Chest X-ray)
- Requiring IV vasoactive agents (Other than Nesiritide)
- Killip Class III/IV
- Systolic blood pressure \< 90 mmHg
- EKG diagnostic or suggestive of Acute myocardial infarction or ischemia
- Abnormal Cardiac Markers
- Lack of a telephone
- Inability to provide informed consent due to cognitive impairment or a severe psychiatric disorder
Key Trial Info
Start Date :
March 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2007
Estimated Enrollment :
17 Patients enrolled
Trial Details
Trial ID
NCT00453453
Start Date
March 1 2007
End Date
September 1 2007
Last Update
February 9 2015
Active Locations (1)
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1
Grady Memorial Hosptial
Atlanta, Georgia, United States, 30303