Status:

COMPLETED

Pulmonary Function Changes in 10 Pack Year Smokers With Chronic Bronchitis

Lead Sponsor:

Westside Family Medical Center, P.C.

Collaborating Sponsors:

GlaxoSmithKline

Conditions:

Chronic Bronchitis

COPD

Eligibility:

All Genders

40-80 years

Brief Summary

To determine whether an average population of males and females who smoke 10 pack years or more of cigarettes in a primary care setting with chronic bronchitis has already developed significant change...

Detailed Description

The incident of COPD is dramatically increasing while other chronic disease states are decreasing in the US population. Smoking cigarettes is the leading risk factor for COPD. Smokers with chronic bro...

Eligibility Criteria

Inclusion

  • Subjects must sign a written informed consent.
  • Enrollment population would include males and females 40 years of age to 80 years of age.
  • Current history or past history of smoking at least 10 pack years of cigarettes.
  • Patients to satisfy the diagnosis of chronic bronchitis.
  • Non-smokers will be allowed in the control group

Exclusion

  • Chronic infections such as TB or other infections of the lungs.
  • Collagen diseases such as rheumatoid arthritis or lupus which affect the lungs.
  • Any previous lung diseases such as pneumoconiosis.
  • Previous accidents or surgery which would involve the lungs or the ribcage.
  • Maintenance medications used for asthma or COPD such as long acting bronchodilators or inhaled corticosteroids.
  • Asthma patients or other patients with allergies that may affect pulmonary function test will be excluded.
  • Any medical condition in the opinion of the investigator that would make the subject unsuitable for enrollment.
  • Pregnant woman will not be allowed
  • Current participation in a research study or within the last 30 days.

Key Trial Info

Start Date :

March 1 2007

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 1 2008

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT00454675

Start Date

March 1 2007

End Date

August 1 2008

Last Update

August 15 2008

Active Locations (1)

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1

Westside Family Medical Center, P.C.

Kalamazoo, Michigan, United States, 49009