Status:

COMPLETED

Efficacy of an Oral Formula in Prevention of Anti-cancer Therapy Side Effects

Lead Sponsor:

Société des Produits Nestlé (SPN)

Conditions:

Digestive Cancers

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

Anti-cancer treatment is often inducing side-effects that can affect the compliance to the treatment protocol and quality of life of the patients. The researchers will study if the nutritional interve...

Eligibility Criteria

Inclusion

  • Patient with GI neoplasm
  • Patient that must start a (new) line of chemotherapy with at least 2 cycles
  • Age \> 18 ans
  • Exclusively orally fed
  • Life expectancy more than 3 months
  • Intravenous 5FU-based chemotherapy with 2 or 3-week cycles
  • Hematological toxicities from previous chemotherapies terminated or \<= 2

Exclusion

  • Positive HIV status
  • Pregnant or lactating woman
  • Currently participating or having participated in another clinical trial during the last month prior to the beginning of this study
  • Patient having diarrhoea of grade \> 1 for more than 2 weeks before the inclusion
  • State of sub occlusion, chronic inflammatory diseases of the digestive tract, radiation enteropathy
  • Sepsis
  • Concomitant radiotherapy, except analgesic radiotherapy

Key Trial Info

Start Date :

October 1 2007

Trial Type :

INTERVENTIONAL

End Date :

January 1 2012

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00455247

Start Date

October 1 2007

End Date

January 1 2012

Last Update

June 5 2013

Active Locations (7)

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Page 1 of 2 (7 locations)

1

Institut Sainte-Catherine

Avignon, France

2

CH Béziers

Béziers, France

3

CRLCC Léon Bérard

Lyon, France, 69008

4

CRLC Val d'Aurelle

Montpellier, France, 34090