Status:

COMPLETED

Effects of Soy Protein on Serum paraoxonase1 Activity and Lipoproteins in Postmenopausal Women

Lead Sponsor:

Iran University of Medical Sciences

Conditions:

Postmenopausal

Hyperlipidemia

Eligibility:

FEMALE

51-57 years

Phase:

NA

Brief Summary

paraoxonase 1 is involved to prevent LDL and HDL oxidation,so increase of it's activity leads to lower risk of coronary heart disease.In postmenopausal women ,we have decrease of paraoxonase1 activity...

Detailed Description

In a double blind clinical randomised clinical trial with parallel design this study was done.52 postmenopausal women were randomly assigned to 50 g/d soy protein or placebo for 10 weeks.serum lipopro...

Eligibility Criteria

Inclusion

  • Cessation of menes for more than 1 year, elevation for more than 1 year
  • Elevation of FSH level
  • Total cholesterol
  • Triglyceride more than 200 mg/dl

Exclusion

  • Chronic disease (heart disease, cancer, diabetes, hepatic, kidney and thyroid disease)
  • Antihypertensive drugs
  • Antibiotics
  • Lipid lowering drugs
  • Sex hormone treatment
  • Hysterectomy
  • Diet rich in soy protein

Key Trial Info

Start Date :

January 1 2006

Trial Type :

INTERVENTIONAL

End Date :

August 1 2006

Estimated Enrollment :

42 Patients enrolled

Trial Details

Trial ID

NCT00457262

Start Date

January 1 2006

End Date

August 1 2006

Last Update

April 6 2007

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