Status:
COMPLETED
A Comparison Study of the Efficacy of Quetiapine and Haloperidol in Agitated Adults in Emergency Room
Lead Sponsor:
University of Southern California
Collaborating Sponsors:
AstraZeneca
Conditions:
Agitation
Eligibility:
All Genders
18-60 years
Phase:
PHASE4
Brief Summary
In the Psychiatric Emergency Room, agitated patients are treated routinely with an I.M. Haloperidol "cocktail" (Haloperidol 5 mg, Lorazepam 2 mg, Cogentin 2 mg), which has proved to be an effective tr...
Detailed Description
In the Psychiatric Emergency Room, agitated patients are treated routinely with an I.M. Haloperidol "cocktail" (Haloperidol 5 mg, Lorazepam 2 mg, Cogentin 2 mg), which has proved to be an effective tr...
Eligibility Criteria
Inclusion
- English or Spanish speaking patients
- Provision of written informed consent-English and Spanish
- Males and females age 18 to 60 years. Females who are pregnant by inspection should not be included.
- Provision at diagnosis meeting the Diagnostic and Statistical Manual of Mental Disorder, 4th edition (DSM-IV) criteria for Axis I documented who present in an agitated state. PANSS-EC score should be \>15.
- Ability, in the treating physician's opinion, to co-operate with taking oral medication
Exclusion
- Pregnant females who will thus receive routine care in the treating physician's opinion
- Unstable medical illness
- Withdrawal stage from any illicit drugs
- Psychosis that prohibits participation in trial
- Females of childbearing age where pregnancy cannot be confirmed or denied by screening
- Patients who required continued intervention or prolonged restraint
Key Trial Info
Start Date :
May 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2009
Estimated Enrollment :
72 Patients enrolled
Trial Details
Trial ID
NCT00457366
Start Date
May 1 2006
End Date
May 1 2009
Last Update
July 26 2019
Active Locations (1)
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1
Los Angeles County Hospital
Los Angeles, California, United States, 90033