Status:
COMPLETED
The Influence of Hypnotic Medications on Sleep Arousal and Its Effect on Gastroesophageal Reflux
Lead Sponsor:
Thomas Jefferson University
Collaborating Sponsors:
AstraZeneca
Conditions:
Gastroesophageal Reflux
Eligibility:
All Genders
18+ years
Brief Summary
This is a continuation of a study that has already been completed in the division of gastroenterology (GI) looking at the effects of sleep medication zolpidem (Ambien) on subjects with Gastroesophagea...
Detailed Description
The use of hypnotic medications for the treatment of insomnia has increased as has the incidence of gastroesophageal reflux disease (GERD) and its complications. Nocturnal acid reflux is associated wi...
Eligibility Criteria
Inclusion
- Subjects must have had a pH probe test at Thomas Jefferson University between July 2004 and January 2006 with findings consistent with GERD.
- Male or female over the age of 18
Exclusion
- Hypersensitivity to zolpidem or any of its components
- Pregnancy
- History of depression or hypnotic/substance abuse
- Prior esophagus or stomach surgery
- GI tract motility disorder
- Any sleep disorder or contraindications to the use of hypnotic medications.
Key Trial Info
Start Date :
March 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2008
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT00462137
Start Date
March 1 2006
End Date
March 1 2008
Last Update
August 5 2019
Active Locations (1)
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1
Thomas Jefferson University
Philadelphia, Pennsylvania, United States, 19107