Status:
COMPLETED
Hyperbaric Oxygen, Oxidative Stress, NO Bioavailability and Tissue Oxygenation
Lead Sponsor:
Assaf-Harofeh Medical Center
Conditions:
Diabetic Foot Ulcers
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Hyperbaric oxygen therapy (HBOT) increases tissue oxygenation and serves as an adjunct therapy for diabetic wounds. However, some patients have insufficient increase or even paradoxical decrease in ti...
Eligibility Criteria
Inclusion
- diabetic patients, aged 18 years or older, with non-healing foot ulcers
Exclusion
- Patients with macrovascular disease amenable for revascularization with more than 70% obstruction in femoral artery (evaluated by US doppler) were excluded from the study. Similarly, patients with a documented allergy to NAC, liver cirrhosis or those receiving NAC for other indications were excluded. Finally, patients with chest pathology incompatible with pressure changes, patients with inner ear disease, or those suffering from claustrophobia were excluded.
Key Trial Info
Start Date :
December 1 2003
Trial Type :
INTERVENTIONAL
End Date :
September 1 2005
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00463671
Start Date
December 1 2003
End Date
September 1 2005
Last Update
October 17 2008
Active Locations (1)
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1
The Institute of Hyperbaric Medicine and Wound Care Clinic
Ẕerifin, Israel, 70300