Status:
COMPLETED
Effect of Burn Size on Cytomegalovirus Reactivation and Correlates of T Cell Immune Function in Burned Patients
Lead Sponsor:
University of North Carolina, Chapel Hill
Conditions:
Burns
Cytomegalovirus
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this study is to evaluate the effect of burn injury on the human immune system with a focus on cytomegalovirus (CMV) reactivation and the immunologic correlates of latent viral reactiva...
Detailed Description
The purpose of this research study is to learn about infections and the immune system in people who suffer from burn injuries. The immune system changes after burn injury and infection is one of the m...
Eligibility Criteria
Inclusion
- Burn injury,
- Positive CMV IgG level confirmative of previous CMV infection and latency.
Exclusion
- Immunocompromising conditions including HIV/AIDS,
- End-stage renal disease,
- End-stage liver disease,
- Pregnancy,
- Rheumatologic or collagen-vascular disease requiring chronic use of steroids,
- Chronic use of immunosuppressive agents,
- Recent chemotherapy, and
- History of solid organ or allogeneic stem cell transplant.
Key Trial Info
Start Date :
March 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2011
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00467532
Start Date
March 1 2007
End Date
March 1 2011
Last Update
January 17 2013
Active Locations (1)
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1
North Carolina Jaycee Burn Center, UNC Hospitals
Chapel Hill, North Carolina, United States, 27514