Status:
COMPLETED
Efficacy and Safety of Continuous Intravenous Versus Usual Subcutaneous Insulin in Acute Ischemic Stroke
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Acute Stroke
Acute Cerebral Ischemia
Eligibility:
All Genders
19+ years
Phase:
PHASE2
PHASE3
Brief Summary
Hyperglycaemia is a frequent finding in acute ischemic stroke and associated with poor outcome. But the modalities of glucose lowering are still debated. This study will test the efficacy and safety o...
Detailed Description
It is demonstrated that post-stroke hyperglycaemia is associated with poor outcome. Yet, the efficiency of aggressive insulin serum glucose control is not established. Furthermore the modalities of in...
Eligibility Criteria
Inclusion
- Age over 18 years
- Carotid territory stroke
- MRI performed in the first five hours of stroke onset
- Baseline National Institutes of Health Stroke Scale (NIHSS) \> 4 or \< 26
- Time between MRI and treatment under one hour
Exclusion
- Pre-existing Modified Rankin Scale of three or higher
- Advanced or terminal illness with risk of death in the next 6 months, addiction
Key Trial Info
Start Date :
May 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2012
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT00472381
Start Date
May 1 2007
End Date
June 1 2012
Last Update
June 5 2014
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
AP-HP Urgences cerebro vasculaires La Pitié Salpétrière
Poissy, France, 75013