Status:

WITHDRAWN

Safety Assessment of Lactobacillus Fermented Extract in Cancer Patients Undergoing Chemotherapy

Lead Sponsor:

New Hope Medical Center

Conditions:

Cancer

Eligibility:

All Genders

18-75 years

Phase:

EARLY_PHASE1

Brief Summary

Project: Assessment of the safety of dietary supplement lactobacillus fermented extract in cancer patients undergoing chemotherapy Nausea and vomiting are significant causes of nutritional depletion ...

Detailed Description

Randomization and Treatment: The subjects will be distributed in each of the three cancer categories (breast, lung, and colon), and randomized on centralized randomization lists for each of the cancer...

Eligibility Criteria

Inclusion

  • Eligible subjects have given written informed consent prior to participation
  • They must have a life expectancy of greater than 6 months
  • They must have biopsy confirmed primary breast, colon or lung cancer
  • They are receiving standard chemotherapy in accordance with American Society Clinical Oncology (ASCO) standards and have at least one month remaining in their chemotherapy course
  • They must have an Eastern Cooperative Oncology Group (ECOG) performance status \< 2 and are being treated as outpatients.
  • Subjects must be between the ages of 18 to 75 years of age.
  • Subjects must be able to communicate in English.

Exclusion

  • Have received radiotherapy within the last 4 weeks
  • Have acute gastrointestinal problems e.g. acute gastrointestinal infection, gastric or duodenal ulcer, history of bowel obstruction, diverticulitis, Crohn's disease, ulcerative colitis, or chronic diarrhea
  • Presence or clinical evidence of CNS metastases
  • Receiving corticosteroids
  • Have severe concomitant disease
  • Have severe dysphagia, esophagitis or xerostoma

Key Trial Info

Start Date :

January 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2009

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00606970

Start Date

January 1 2007

End Date

December 1 2009

Last Update

May 7 2013

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