Status:

COMPLETED

Study Comparing Two Types of Ports in Patients With Cancer Receiving Intravenous Chemotherapy

Lead Sponsor:

Mayo Clinic

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Unspecified Adult Solid Tumor, Protocol Specific

Vascular Access Device Complications

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

RATIONALE: Giving chemotherapy drugs through an implanted port reduces the need for multiple needle sticks. It is not yet known whether one type of port is more effective than another in reducing infe...

Detailed Description

OBJECTIVES: Primary * To compare the rate of port failure, defined as the occurrence of port malfunction or port infection within 12 months after port insertion, in patients with cancer requiring lo...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Diagnosis of malignancy requiring intravenous chemotherapy for ≥ 6 months
  • Must undergo entire course of chemotherapy at the Mayo Clinic in Jacksonville, unless the outside treating institution agrees to submit the research data sheet to Mayo Clinic
  • Scheduled time frame for regular use of the vascular access port ≥ 3 months after port insertion
  • PATIENT CHARACTERISTICS:
  • Life expectancy ≥ 6 months
  • No active skin condition implicating an elevated risk of local or systemic infectious or non-infectious complications, including any of the following:
  • Current skin infection
  • Cutaneous lymphoma
  • Auto-immune disorders
  • Active vasculitis
  • Connective tissue diseases
  • No known active infection requiring antibiotic therapy at the time of port implantation
  • Patients without an active infection who are on chronic antibiotic suppressive therapy are eligible
  • No concurrent illness requiring chronic anticoagulation
  • Patients who develop other comorbidities requiring chronic anticoagulation during the study period are eligible
  • PRIOR CONCURRENT THERAPY:
  • See Disease Characteristics

Exclusion

    Key Trial Info

    Start Date :

    June 1 2004

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    March 1 2009

    Estimated Enrollment :

    100 Patients enrolled

    Trial Details

    Trial ID

    NCT00607880

    Start Date

    June 1 2004

    End Date

    March 1 2009

    Last Update

    May 9 2014

    Active Locations (1)

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    Mayo Clinic - Jacksonville

    Jacksonville, Florida, United States, 32224