Status:
COMPLETED
Effect of Dietary Conjugated Linoleic Acid (CLA) on Parathyroid Hormone in Men
Lead Sponsor:
McGill University
Conditions:
Healthy
Eligibility:
MALE
19-53 years
Phase:
PHASE1
Brief Summary
The parathyroid gland and its hormone have a major impact on the endocrine control of bone metabolism and mineralization and parathyroid hormone (PTH) has been identified in some epidemiological repor...
Detailed Description
EXPERIMENTAL DETAILS The global objective of this study is to, for the first time; assess the effects of CLA on PTH in humans, specifically men. Primary Objectives and Hypotheses, in healthy men 40 y...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- The sample size will be 90 healthy men (n=30/group) based on the following inclusion criteria:
- Healthy body weight based on body mass index (18.5 - 25 kg/m2 as per Health Canada
- No chronic diseases
- Normal bone mass for age (ie Z-score better than -1 where reference data available)
- Vitamin D status within optimal range based on serum 25(OH)D (between 50 and 80 nmol/L of serum 25(OH)D with a median threshold of 75 nmol/L as set by international experts.
Exclusion
Key Trial Info
Start Date :
December 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2011
Estimated Enrollment :
55 Patients enrolled
Trial Details
Trial ID
NCT00608400
Start Date
December 1 2008
End Date
December 1 2011
Last Update
March 2 2012
Active Locations (1)
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1
Mary Emily Clinical Nutrition Research Unit
Sainte-Anne-de-Bellevue, Quebec, Canada, H9X 3V9