Status:

COMPLETED

Prevalence+Significance of Paraneoplastic Autoantibodies in Many Cancers

Lead Sponsor:

Memorial Sloan Kettering Cancer Center

Conditions:

Lung Cancer

Ovarian Cancer

Eligibility:

All Genders

Brief Summary

You may have a type of cancer associated with "antineuronal antibodies" in your blood. Antibodies are substances made by the immune system. They are used by the body to fight infections and other dis...

Detailed Description

Objectives: To determine prospectively the prevalence and specificity of anti-Hu and other paraneoplastic antibodies in patients with small cell lung cancer (SCLC) and other cancers including, but no...

Eligibility Criteria

Inclusion

  • Patients with previous cancers or concurrent cancers. Patient has or may have, newly-diagnosed or recurrent SCLC, or mixed small cell/non small cell lung cancer, or neuroblastoma, or ovarian or breast cancer, or Hodgkin's disease in all cases confirmed by pathological review.

Exclusion

  • Patient refusal to participate in follow-up clinical evaluations. For minors, parental or guardian refusal.
  • Patient refusal to provide blood samples for autoantibody determinations and HLA typing (total 4 tubes).

Key Trial Info

Start Date :

July 1 1995

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 1 2009

Estimated Enrollment :

121 Patients enrolled

Trial Details

Trial ID

NCT00608452

Start Date

July 1 1995

End Date

November 1 2009

Last Update

November 13 2009

Active Locations (1)

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1

Memorial Sloan Kettering Cancer Center

New York, New York, United States, 10065