Status:
COMPLETED
Effects of Environmental Factors on Opiate Drug Choice in Opioid Dependent Individuals.
Lead Sponsor:
Wayne State University
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
Heroin Dependence
Opioid-Related Disorders
Eligibility:
All Genders
18-55 years
Brief Summary
The purpose is to study how certain factors, including money, the amount of drug available and the amount of work effort, affect opiate drug choice.
Detailed Description
A drug dependent person chooses to take drug more often (and suffer its long-term bad consequences) than choosing to engage in healthy activities (which have better long-term consequences). The presen...
Eligibility Criteria
Inclusion
- Opioid dependent, as determined by structured clinical interview for DSM-IV (SCID) and Addiction Severity Index (ASI)
- Positive urine test for opiates
- Willing to use an adequate form of contraception for the duration of the study.
- Reads and writes English
Exclusion
- Psychiatric illness, as determined by the DSM-IV criteria
- History of or current neurological disease, including structural abnormalities, seizures, infection, peripheral neuropathy, and head traumas
- History of cardiovascular disease, myocardial infarction, chest pain, or edema
- Systolic blood pressure greater than 160mm HG or less than 95 mm HG: PR diastolic blood pressure greater than 95 mm HG.
- Pulmonary disease, including obstructive pulmonary disease, Cor pulmonale, tuberculosis, and asthma
- Systemic disease (e.g. endocrinopathies, liver or kidney failure, myxedema, hypothyroidism, Addison's disease, autoimmune disease)
- Current alcohol or sedative drug dependence
- Pregnant or breast feeding
- Currently receiving treatment for opioid dependence
- Known phobia of injections
Key Trial Info
Start Date :
July 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 1 2009
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT00608504
Start Date
July 1 2007
End Date
April 1 2009
Last Update
June 5 2012
Active Locations (1)
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1
Wayne State University
Detroit, Michigan, United States, 48202